Exercise found to lower cardiovascular disease risk by 23%: study

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NEW YORK, April 17: A recent study, led by researchers at Massachusetts General Hospital and published in the Journal of the American College of Cardiology, sheds light on the significant impact of physical activity on stress reduction and its potential to protect against cardiovascular disease (CVD).

Examining the medical records of over 50,000 individuals from the Mass General Brigham Biobank, researchers analyzed the correlation between physical activity levels and the development of CVD over a median follow-up period of 10 years. Additionally, a subset of 774 participants underwent brain imaging tests to assess stress-related brain activity.

The findings unveiled a promising relationship between physical exercise and cardiovascular health. Participants who achieved recommended levels of physical activity experienced a 23% lower risk of developing CVD compared to those with sedentary lifestyles.

Moreover, the study revealed an inverse association between physical activity and stress-related brain activity. Higher levels of exercise were linked to reduced levels of stress-related brain activity, particularly benefiting individuals with stress-related conditions such as depression.

Dr. Ahmed Tawakol, MD, a cardiologist involved in the research, highlighted the significant role of exercise in lowering cardiovascular risk, especially among individuals with depression. He emphasized that exercise was approximately twice as effective in reducing CVD risk in this group.

Cardiovascular disease remains a leading cause of mortality globally, with a significant portion of deaths attributed to stroke or heart attack. The study’s findings underscore the importance of addressing stress and promoting physical activity to mitigate the risk of CVD.

Experts not involved in the study emphasized the bidirectional relationship between depression and heart disease. Stress-related brain activity, common in conditions like depression and anxiety, can exacerbate cardiovascular risk factors. Conversely, exercise offers natural benefits in regulating brain chemistry, reducing inflammation, and improving mood, thereby contributing to cardiovascular health.

While medications for depression target neurotransmitters in the brain, exercise offers holistic benefits by positively impacting both mental and physical well-being. Understanding the intertwined relationship between physical activity, stress reduction, and cardiovascular health underscores the importance of incorporating regular exercise into daily routines for overall well-being and heart health.

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