New findings suggest even low doses of paracetamol may harm heart health

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NEW YORK, April 15: Recent research has unveiled concerning insights into the potential risks associated with even minor doses of paracetamol, commonly known as acetaminophen. Scientists in the United States have discovered that this widely available over-the-counter medication, commonly used in the UK and sold in supermarkets globally, could adversely affect the heart.

According to findings presented at the American Physiology Summit in Long Beach, California, researchers from the University of California, Davis, have revealed that regular use of paracetamol, even at safe doses, can lead to significant alterations in various signaling pathways within the heart tissue. Dr. Gabriela Rivera, one of the lead researchers, highlighted, “We found that regular use of acetaminophen at concentrations that are considered safe — equivalent to 500 mg/day — causes numerous signaling pathways inside the heart to be altered.”

The study, which involved administering paracetamol to mice over seven days, observed notable changes in the levels of proteins associated with biochemical pathways crucial for heart function. Such alterations serve as indicators of the heart’s overall health and functionality.

Furthermore, the research suggests that prolonged use of medium to high doses of paracetamol could potentially lead to heart issues due to oxidative stress or the accumulation of toxins. Concerns have been raised regarding the long-term implications of paracetamol consumption on heart health.

In response to these findings, experts advise caution and recommend the use of paracetamol at the lowest effective dose and for the shortest duration possible. The National Health Service (NHS) guidelines specify the maximum dosage of paracetamol for adults, emphasizing the importance of adhering to recommended limits to minimize the risk of adverse effects.

As further research continues to explore the implications of paracetamol on cardiovascular health, individuals are urged to exercise prudence and consult healthcare professionals regarding appropriate usage and potential risks associated with this widely used painkiller.

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