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Baby born to couple with chromosomal abnormality – First in Gulf region

ABU DHABI, UAE, June 4: A Middle- Eastern couple with chromosomal abnormality and parental consanguinity is the first in the region to be blessed with an absolutely healthy baby. Born in June 2016 to 34-year-old Aliya and 37-year-old Mehdi, who were treated at IVI Middle East Fertility Clinic, the baby was born to the couple after 10 years of trying to be parents.

While Mehdi’s chromosomal abnormality prevented sperm production, Aliya had a reduced ovarian reserve due to parental consanguinity.

At IVI, the couple received accurate diagnosis of their problem through personalised consultations and a whole range of individualised treatments which offered best results. With the right treatment approach, Mehdi’s sperm was found naturally without the need for a surgery.

Following that IVF was performed accompanied with genetic testing on the embryos, which led to the successful pregnancy. “The reasons of male and female infertility are very different here in the Middle East as compared to other countries. Parental consanguinity leads to a poor ovarian reserve in women trying to conceive. Success for IVI Fertility starts with the correct diagnosis.

Because if the problem is addressed, the chances of a healthy conception are much higher,” said Prof Dr Human Fatemi , Subspecialist Reproductive Medicine & Reproductive Surgery, Medical Director, IVI Middle East Fertility Clinic. A newly released study published by IVI Fertility Middle East shows that consanguineous couples (those marrying first or second-degree relatives) are a major cause of high infertility in the Gulf region as well as they are at a higher risk of having a baby with genetic abnormalities.

However, the good news lies in the fact that if detected earlier, a huge percentage of such birth defects can be prevented. “In the GCC, the cultural acceptance of consanguinity has resulted in its high prevalence (almost 50 per cent) in the region, and has evolved to be one of the primary causes of genetic disorders. Parental consanguinity has been associated with both male and female infertility. In females, it prematurely reduces the ovarian reserve, which is the bank of fertile eggs in women.

Amongst males it causes chromosome Y abnormalities, leading to genetic sperm defects,” added Prof Dr Human Fatemi. Passing on of genetic disorders to the child can be eliminated if detected correctly. IVI Middle East Fertility Clinic offers a highly advanced genetic test called the Compatibility Genetic Test (CGT) which is exclusively available only at IVI Middle East Fertility Clinic. The test help couples find out if they carry genetic mutations that can be passed on to their children. This is done through a simple blood test and is highly recommended to all couples who are attempting a pregnancy by natural or IVF means. It is the most responsible way to plan your family.

Another couple, Hamid and Fatima, who reside in Dubai, highlighted the key significance of (CGT). “Hamid had a family history of Alström Syndrome. After we got married we were sure we didn’t want to pass on the disease to our child. That’s when we came across the highly advanced Compatibility Genetic Test (CGT) at IVI Middle East. Thanks to IVI and Dr. Fatemi’s specialised research in the GCC, we are finally blessed with a healthy baby girl,” said Fatema (name changed), a 28-year-old Emirati woman residing in Dubai. Compatibility Genetic Test (CGT) allows genetic testing of a couple, prior to conception and eliminates possibilities of genetically transmitted diseases in babies.

IVI Middle East Fertility Clinic’s thorough understanding of the region and its use of advanced technologies in infertility treatments has enabled it to achieve more than 200 successful pregnancies within a short span. “Given the fact that a large percentage of people in the GCC are prone to genetic abnormalities, a Compatibility Genetic Test (CGT) is highly recommended. Generally, parents only realise they are carriers of serious genetic disorders after an affected child is born. Genetic disorders can’t be cured, but they can be prevented. With this test, couples can be assured of a healthy pregnancy. If both partners test positive in a Compatibility Genetic Test (CGT) with the same gene mutation, the recommendation is to undertake an IVF procedure and eliminate a genetically effected embryo by PGS screening. Healthy embryos have an enhanced chance of a successful pregnancy and a healthy baby”, added Prof Dr Human Fatemi.

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