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Thursday, February 26, 2026
 
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Breakthrough in Diabetes: China Achieves Milestone in Reversing Type 2 Diabetes

publish time

25/02/2026

publish time

25/02/2026

SHANGHAI, Feb 25: Here’s something big: scientists in China have actually reversed type 2 diabetes using stem-cell therapy. It’s a major step forward, not just for them, but for the world. For the first time, a patient with type 2 diabetes came off insulin injections and other meds, all thanks to transplanted pancreatic cells. These new cells did what insulin usually does in the body, and the patient could keep their blood sugar in check without outside help.

So, what’s the deal with type 2 diabetes?
Basically, the body stops using insulin properly, and blood sugar levels go up. Most people end up relying on insulin shots or pills. And once someone needs daily insulin, getting the body back to normal is almost impossible—at least, that’s what we thought.

Here’s how the researchers pulled this off
They started by getting stem cells, either from the patient or a donor. What makes stem cells special is that you can turn them into all sorts of specialized cells—in this case, pancreatic islet cells (specifically beta cells), which are the ones that naturally pump out insulin.

In the lab, scientists bathe these stem cells in just the right mix of chemicals and genetic cues, training them to become those insulin-producing beta cells. They grow these into little clusters that look and act like actual pancreatic tissue. These clusters can sense when blood sugar rises and pump out insulin to bring it down.

Next, doctors transplant these insulin-making clusters into the patient’s body, usually somewhere in the abdomen. The hope is that these new cells hook up with the patient’s blood supply and start working for real. The big question is always whether the patient’s immune system will accept or reject the new cells—get that wrong, and the treatment fails.

If all goes well, the transplanted cells kick in and start doing the job of healthy beta cells. The patient’s body senses when sugar goes up and releases insulin, no injections needed. Some people might be able to cut back on insulin, while others can stop it completely.

After the transplant, doctors keep a close eye on things—making sure the new cells are still alive, still making insulin, and not causing any weird immune problems. This stem cell approach could be a game-changer, offering people with type 2 diabetes a shot at long-term, personalized treatment that goes way beyond the usual meds.